Загрузка...

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7

IL-7 is pivotal for B cell development. Proteins of the Bcl-2 family are essential regulators of lymphocyte survival. Particularly, the pro-apoptotic BH3-only members Bim and Puma mediate lymphocyte apoptosis provoked by cytokine deprivation. Herein, we addressed whether the absence of Bim or Puma w...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Huntington, Nicholas D., Labi, Verena, Cumano, Ana, Vieira, Paulo, Strasser, Andreas, Villunger, Andreas, Di Santo, James P., Alves, Nuno L.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980998/
https://ncbi.nlm.nih.gov/pubmed/19454543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxp043
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!