Loss of the Pro-Apoptotic BH3-only Bcl-2 Family Member Bim Inhibits BCR Stimulation–induced Apoptosis and Deletion of Autoreactive B Cells

During development, the stochastic process assembling the genes encoding antigen receptors invariably generates B and T lymphocytes that can recognize self-antigens. Several mechanisms have evolved to prevent the activation of these cells and the concomitant development of autoimmune disease. One su...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Enders, Anselm, Bouillet, Philippe, Puthalakath, Hamsa, Xu, Yuekang, Tarlinton, David M., Strasser, Andreas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2003
Aiheet:
Brief Definitive Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194219/
https://ncbi.nlm.nih.gov/pubmed/14517273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030411
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