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Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis

The BH3-only proteins of the Bcl-2 family initiate apoptosis through the activation of Bax-like relatives. Loss of individual BH3-only proteins can lead either to no phenotype, as in mice lacking Bik, or to marked cell excess, as in the hematopoietic compartment of animals lacking Bim. To investigat...

詳細記述

保存先:
書誌詳細
主要な著者: Coultas, Leigh, Bouillet, Philippe, Loveland, Kate L, Meachem, Sarah, Perlman, Harris, Adams, Jerry M, Strasser, Andreas
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283956/
https://ncbi.nlm.nih.gov/pubmed/16270031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600857
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