Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice

The pro-apoptotic BH3-only BCL-2 family member BIM is a critical determinant of hematopoietic cell development and homeostasis. It has been argued that the striking hematopoietic abnormalities of BIM-deficient mice (accumulation of lymphocytes and granulocytes) may be the result of the loss of the p...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Herold, M J, Stuchbery, R, Mérino, D, Willson, T, Strasser, A, Hildeman, D, Bouillet, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237241/
https://ncbi.nlm.nih.gov/pubmed/25299771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.409
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