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Bim must be able to engage all pro-survival Bcl-2 family members for efficient tumor suppression
Over-expression of the transcriptional regulator Myc is thought to be the cause or a contributing factor in the development of a large number of human lymphomas and certain other cancers. Apoptotic cell death constitutes a tumor suppressive mechanism, particularly in the context of Myc over-expressi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361534/ https://ncbi.nlm.nih.gov/pubmed/22081075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.508 |
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