GM-CSF CAUSES A PARADOXICAL INCREASE IN THE BH3-ONLY PRO-APOPTOTIC PROTEIN BIM IN HUMAN NEUTROPHILS

Neutrophil apoptosis is essential for the resolution of inflammation but delayed by several inflammatory mediators. In such terminally differentiated cells it has been uncertain whether these agents can inhibit apoptosis through transcriptional regulation of anti-death (Bcl-X(L), Mcl-1, Bcl2A1) or B...

Full description

Saved in:
Bibliographic Details
Published in:Am J Respir Cell Mol Biol
Main Authors: Cowburn, Andrew S, Summers, Charlotte, Dunmore, Benjamin J, Farahi, Neda, Print, Cristin G, Cook, Simon J, Chilvers, Edwin R
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373550/
https://ncbi.nlm.nih.gov/pubmed/20705940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0101OC
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items