Correction of Nonsense BMPR2 and SMAD9 Mutations by Ataluren in Pulmonary Arterial Hypertension

Por Drake, Kylie M., Dunmore, Benjamin J., McNelly, Lauren N., Morrell, Nicholas W., Aldred, Micheala A.
Publicado em 2013

MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms

Por Affara, Muna, Dunmore, Benjamin J, Sanders, Deborah A, Johnson, Nicola, Print, Cristin G, Charnock-Jones, D Stephen
Publicado em 2011

The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations

Por Dunmore, Benjamin J., Drake, Kylie M., Upton, Paul D., Toshner, Mark R., Aldred, Micheala A., Morrell, Nicholas W.
Publicado em 2013

GM-CSF CAUSES A PARADOXICAL INCREASE IN THE BH3-ONLY PRO-APOPTOTIC PROTEIN BIM IN HUMAN NEUTROPHILS

Por Cowburn, Andrew S, Summers, Charlotte, Dunmore, Benjamin J, Farahi, Neda, Print, Cristin G, Cook, Simon J, Chilvers, Edwin R
Publicado no Am J Respir Cell Mol Biol (2010)

Caveolae protect endothelial cells from membrane rupture during increased cardiac output

Por Cheng, Jade P.X., Mendoza-Topaz, Carolina, Howard, Gillian, Chadwick, Jessica, Shvets, Elena, Cowburn, Andrew S., Dunmore, Benjamin J., Crosby, Alexi, Morrell, Nicholas W., Nichols, Benjamin J.
Publicado no J Cell Biol (2015)

Contributions of BMPR2 Mutations and Extrinsic Factors to Cellular Phenotypes of Pulmonary Arterial Hypertension Revealed by Induced Pluripotent Stem Cell Modeling

Por Kiskin, Fedir N., Chang, C-Hong, Huang, Christopher J. Z., Kwieder, Baraa, Cheung, Christine, Dunmore, Benjamin J., Serrano, Felipe, Sinha, Sanjay, Morrell, Nicholas W., Rana, Amer A.
Publicado no Am J Respir Crit Care Med (2018)

Vasohibin-1 is identified as a master-regulator of endothelial cell apoptosis using gene network analysis

Por Affara, Muna, Sanders, Debbie, Araki, Hiromitsu, Tamada, Yoshinori, Dunmore, Benjamin J, Humphreys, Sally, Imoto, Seiya, Savoie, Christopher, Miyano, Satoru, Kuhara, Satoru, Jeffries, David, Print, Cristin, Charnock-Jones, D Stephen
Publicado em 2013

Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets

Por Sandovici, Ionel, Hammerle, Constanze M., Cooper, Wendy N., Smith, Noel H., Tarry-Adkins, Jane L., Dunmore, Benjamin J., Bauer, Julien, Andrews, Simon R., Yeo, Giles S. H., Ozanne, Susan E., Constância, Miguel
Publicado no Diabetologia (2015)

Identification of a Lysosomal Pathway Regulating Degradation of the Bone Morphogenetic Protein Receptor Type II

Por Durrington, Hannah J., Upton, Paul D., Hoer, Simon, Boname, Jessica, Dunmore, Benjamin J., Yang, Jun, Crilley, Trina K., Butler, Lynn M., Blackbourn, David J., Nash, Gerard B., Lehner, Paul J., Morrell, Nicholas W.
Publicado em 2010

Transcript Analysis Reveals a Specific HOX Signature Associated with Positional Identity of Human Endothelial Cells

Por Toshner, Mark, Dunmore, Benjamin J., McKinney, Eoin F., Southwood, Mark, Caruso, Paola, Upton, Paul D., Waters, John P., Ormiston, Mark L., Skepper, Jeremy N., Nash, Gerard, Rana, Amer A., Morrell, Nicholas W.
Publicado em 2014

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling

Por Hurst, Liam A., Dunmore, Benjamin J., Long, Lu, Crosby, Alexi, Al-Lamki, Rafia, Deighton, John, Southwood, Mark, Yang, Xudong, Nikolic, Marko Z., Herrera, Blanca, Inman, Gareth J., Bradley, John R., Rana, Amer A., Upton, Paul D., Morrell, Nicholas W.
Publicado no Nat Commun (2017)

Identification of miR-124 as a major regulator of enhanced endothelial cell glycolysis in pulmonary arterial hypertension via PTBP1 and PKM2

Por Caruso, Paola, Dunmore, Benjamin J., Schlosser, Kenny, Schoors, Sandra, Santos, Claudia Dos, Perez-Iratxeta, Carol, Lavoie, Jessie R., Zhang, Hui, Long, Lu, Flockton, Amanda R., Frid, Maria G., Upton, Paul D., D’Alessandro, Angelo, Hadinnapola, Charaka, Kiskin, Fedir N., Taha, Mohamad, Hurst, Liam A., Ormiston, Mark L., Hata, Akiko, Stenmark, Kurt R., Carmeliet, Peter, Stewart, Duncan J., Morrell, Nicholas W.
Publicado no Circulation (2017)