Identification of a Lysosomal Pathway Regulating Degradation of the Bone Morphogenetic Protein Receptor Type II

Bone morphogenetic proteins (BMPs) are critically involved in early development and cell differentiation. In humans, dysfunction of the bone morphogenetic protein type II receptor (BMPR-II) is associated with pulmonary arterial hypertension (PAH) and neoplasia. The ability of Kaposi sarcoma-associat...

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Bibliographic Details
Main Authors: Durrington, Hannah J., Upton, Paul D., Hoer, Simon, Boname, Jessica, Dunmore, Benjamin J., Yang, Jun, Crilley, Trina K., Butler, Lynn M., Blackbourn, David J., Nash, Gerard B., Lehner, Paul J., Morrell, Nicholas W.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988369/
https://ncbi.nlm.nih.gov/pubmed/20870717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132415
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