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Regulation of Bone Morphogenetic Protein 9 (BMP9) by Redox-dependent Proteolysis

BMP9, a member of the TGFβ superfamily, is a homodimer that forms a signaling complex with two type I and two type II receptors. Signaling through high-affinity activin receptor-like kinase 1 (ALK1) in endothelial cells, circulating BMP9 acts as a vascular quiescence factor, maintaining endothelial...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wei, Zhenquan, Salmon, Richard M., Upton, Paul D., Morrell, Nicholas W., Li, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223318/
https://ncbi.nlm.nih.gov/pubmed/25237187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.579771
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