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Bone Morphogenetic Protein (BMP) and Activin Type II Receptors Balance BMP9 Signals Mediated by Activin Receptor-like Kinase-1 in Human Pulmonary Artery Endothelial Cells

Mutations in transforming growth factor-β (TGF-β) receptor superfamily members underlie conditions characterized by vascular dysplasia. Mutations in endoglin and activin-like kinase receptor 1 (ALK1) cause hereditary hemorrhagic telangiectasia, whereas bone morphogenetic protein type II receptor (BM...

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Autors principals: Upton, Paul D., Davies, Rachel J., Trembath, Richard C., Morrell, Nicholas W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708876/
https://ncbi.nlm.nih.gov/pubmed/19366699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.002881
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