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Hypoxia and HIF-1α in osteoarthritis
We have previously shown that functional inactivation of hypoxia-inducible factor-1α (HIF-1α) in growth-plate chondrocytes will dramatically inhibit anaerobic energy generation and matrix synthesis. Using immunohistochemistry, we have now analyzed the spatial distribution of HIF-1α and its target ge...
Sparad:
| Huvudupphovsmän: | , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Springer-Verlag
2004
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3456953/ https://ncbi.nlm.nih.gov/pubmed/15611874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00264-004-0618-2 |
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