Hypoxia and HIF-1α in osteoarthritis

We have previously shown that functional inactivation of hypoxia-inducible factor-1α (HIF-1α) in growth-plate chondrocytes will dramatically inhibit anaerobic energy generation and matrix synthesis. Using immunohistochemistry, we have now analyzed the spatial distribution of HIF-1α and its target ge...

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Bibliographic Details
Main Authors: Pfander, David, Cramer, Thorsten, Swoboda, Bernd
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2004
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3456953/
https://ncbi.nlm.nih.gov/pubmed/15611874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00264-004-0618-2
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