Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition

Rationale: Acute respiratory distress syndrome is refractory to pharmacological intervention. Inappropriate activation of alveolar neutrophils is believed to underpin this disease’s complex pathophysiology, yet these cells have been little studied. Objectives: To examine the functional and transcrip...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Juss, Jatinder K., House, David, Amour, Augustin, Begg, Malcolm, Herre, Jurgen, Storisteanu, Daniel M. L., Hoenderdos, Kim, Bradley, Glyn, Lennon, Mark, Summers, Charlotte, Hessel, Edith M., Condliffe, Alison, Chilvers, Edwin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067816/
https://ncbi.nlm.nih.gov/pubmed/27064380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201509-1818OC
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