Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition

Rationale: Acute respiratory distress syndrome is refractory to pharmacological intervention. Inappropriate activation of alveolar neutrophils is believed to underpin this disease’s complex pathophysiology, yet these cells have been little studied. Objectives: To examine the functional and transcrip...

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Bibliografische gegevens
Gepubliceerd in:Am J Respir Crit Care Med
Hoofdauteurs: Juss, Jatinder K., House, David, Amour, Augustin, Begg, Malcolm, Herre, Jurgen, Storisteanu, Daniel M. L., Hoenderdos, Kim, Bradley, Glyn, Lennon, Mark, Summers, Charlotte, Hessel, Edith M., Condliffe, Alison, Chilvers, Edwin R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2016
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067816/
https://ncbi.nlm.nih.gov/pubmed/27064380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201509-1818OC
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