Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

The phagocyte respiratory burst is crucial for innate immunity. The transfer of electrons to oxygen is mediated by a membrane-bound heterodimer, comprising gp91phox and p22phox subunits. Deficiency of either subunit leads to severe immunodeficiency. We describe Eros (essential for reactive oxygen sp...

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Publicado no:J Exp Med
Main Authors: Thomas, David C., Clare, Simon, Sowerby, John M., Pardo, Mercedes, Juss, Jatinder K., Goulding, David A., van der Weyden, Louise, Storisteanu, Daniel, Prakash, Ananth, Espéli, Marion, Flint, Shaun, Lee, James C., Hoenderdos, Kim, Kane, Leanne, Harcourt, Katherine, Mukhopadhyay, Subhankar, Umrania, Yagnesh, Antrobus, Robin, Nathan, James A., Adams, David J., Bateman, Alex, Choudhary, Jyoti S., Lyons, Paul A., Condliffe, Alison M., Chilvers, Edwin R., Dougan, Gordon, Smith, Kenneth G.C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379978/
https://ncbi.nlm.nih.gov/pubmed/28351984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161382
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