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PI3Kδ and primary immunodeficiencies
Primary immunodeficiencies are inherited disorders of the immune system, often caused by the mutation of genes required for lymphocyte development and activation. Recently, several studies have identified gain-of-function mutations in the phosphoinositide 3-kinase (PI3K) genes PIK3CD (which encodes...
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| Udgivet i: | Nat Rev Immunol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291318/ https://ncbi.nlm.nih.gov/pubmed/27616589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2016.93 |
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