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Idelalisib —targeting PI3Kδ in patients with B cell malignancies

Idelalisib, the first PI3Kδ inhibitor in clinical use, has excellent activity in patients with chronic lymphocytic leukaemia and indolent B cell lymphomas, heralding a new era of targeted therapy for these types of cancer. Idelalisib intercepts critical communications between B cells and the microen...

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Detalhes bibliográficos
Publicado no:Nat Rev Clin Oncol
Main Authors: Burger, Jan A., Okkenhaug, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536758/
https://ncbi.nlm.nih.gov/pubmed/24642682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2014.42
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