PI3Kδ and primary immunodeficiencies

Primary immunodeficiencies are inherited disorders of the immune system, often caused by the mutation of genes required for lymphocyte development and activation. Recently, several studies have identified gain-of-function mutations in the phosphoinositide 3-kinase (PI3K) genes PIK3CD (which encodes...

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Detaylı Bibliyografya
Yayımlandı:Nat Rev Immunol
Asıl Yazarlar: Lucas, Carrie L., Chandra, Anita, Nejentsev, Sergey, Condliffe, Alison M., Okkenhaug, Klaus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291318/
https://ncbi.nlm.nih.gov/pubmed/27616589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2016.93
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