Divergent S Phase Checkpoint Activation Arising from Prereplicative Complex Deficiency Controls Cell Survival

Por Lau, Eric, Chiang, Gary G., Abraham, Robert T., Jiang, Wei
Publicado em 2009

The role of Dbf4/Drf1-dependent kinase Cdc7 (Ddk) in DNA damage checkpoint control

Por Tsuji, Toshiya, Lau, Eric, Chiang, Gary G., Jiang, Wei
Publicado no Mol Cell (2008)

Control of mTORC1 signaling by the Opitz syndrome protein MID1

Por Liu, Enbo, Knutzen, Christine A., Krauss, Sybille, Schweiger, Susann, Chiang, Gary G.
Publicado em 2011

Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of Rapamycin

Por Hudson, Christine C., Liu, Mei, Chiang, Gary G., Otterness, Diane M., Loomis, Dawn C., Kaper, Fiona, Giaccia, Amato J., Abraham, Robert T.
Publicado em 2002

Tuberous Sclerosis Complex 1: An Epithelial Tumor Suppressor Essential to Prevent Spontaneous Prostate Cancer in Aged Mice

Por Kladney, Raleigh D., Cardiff, Robert D., Kwiatkowski, David J., Chiang, Gary G., Weber, Jason D., Arbeit, Jeffrey M., Lu, Zhi Hong
Publicado em 2010

Comparative Metabolic Flux Profiling of Melanoma Cell Lines: BEYOND THE WARBURG EFFECT

Por Scott, David A., Richardson, Adam D., Filipp, Fabian V., Knutzen, Christine A., Chiang, Gary G., Ronai, Ze'ev A., Osterman, Andrei L., Smith, Jeffrey W.
Publicado em 2011

REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A–DDB1 ubiquitin ligase

Por Katiyar, Samiksha, Liu, Enbo, Knutzen, Christine A, Lang, Elizabeth S, Lombardo, Christian R, Sankar, Sabita, Toth, Julia I, Petroski, Matthew D, Ronai, Ze'ev, Chiang, Gary G
Publicado em 2009

Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways

Por Feng, Yongmei, Barile, Elisa, De, Surya K., Stebbins, John L., Cortez, Apple, Aza-Blanc, Pedro, Villanueva, Jessie, Heryln, Meenhard, Krajewski, Stan, Pellecchia, Maurizio, Ronai, Ze’ev A., Chiang, Gary G.
Publicado em 2011

mTOR Activator Rheb Is Frequently Overexpressed In Human Carcinomas And Is Critical And Sufficient For Skin Epithelial Carcinogenesis

Por Lu, Zhi Hong, Shvartsman, Mark B., Lee, Andrew Y., Shao, Jenny M., Murray, Mollianne M., Kladney, Raleigh D., Fan, Dong, Krajewski, Stan, Chiang, Gary G., Mills, Gordon B., Arbeit, Jeffrey M.
Publicado em 2010

Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a

Por Sweis, Ramzi F., Pliushchev, Marina, Brown, Peter J., Guo, Jun, Li, Fengling, Maag, David, Petros, Andrew M., Soni, Nirupama B., Tse, Chris, Vedadi, Masoud, Michaelides, Michael R., Chiang, Gary G., Pappano, William N.
Publicado em 2014

Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2

Por Sweis, Ramzi F., Wang, Zhi, Algire, Mikkel, Arrowsmith, Cheryl H., Brown, Peter J., Chiang, Gary G., Guo, Jun, Jakob, Clarissa G., Kennedy, Steven, Li, Fengling, Maag, David, Shaw, Bailin, Soni, Nirupama B., Vedadi, Masoud, Pappano, William N.
Publicado no ACS Med Chem Lett (2015)

The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia

Por Pappano, William N., Guo, Jun, He, Yupeng, Ferguson, Debra, Jagadeeswaran, Sujatha, Osterling, Donald J., Gao, Wenqing, Spence, Julie K., Pliushchev, Marina, Sweis, Ramzi F., Buchanan, Fritz G., Michaelides, Michael R., Shoemaker, Alexander R., Tse, Chris, Chiang, Gary G.
Publicado no PLoS One (2015)

Discovery of a potent catalytic p300/CBP inhibitor that targets lineage-specific tumors

Por Lasko, Loren M., Jakob, Clarissa G., Edalji, Rohinton P., Qiu, Wei, Montgomery, Debra, Digiammarino, Enrico L., Hansen, T. Matt, Risi, Roberto M., Frey, Robin, Manaves, Vlasios, Shaw, Bailin, Algire, Mikkel, Hessler, Paul, Lam, Lloyd T., Uziel, Tamar, Faivre, Emily, Ferguson, Debra, Buchanan, Fritz G., Martin, Ruth L., Torrent, Maricel, Chiang, Gary G., Karukurichi, Kannan, Langston, J. William, Weinert, Brian T., Choudhary, Chunaram, de Vries, Peter, Van Drie, John H., McElligott, David, Kesicki, Ed, Marmorstein, Ronen, Sun, Chaohong, Cole, Philip A., Rosenberg, Saul H., Michaelides, Michael R., Lai, Albert, Bromberg, Kenneth D.
Publicado no Nature (2017)