The ubiquitin system, disease, and drug discovery

Por Petroski, Matthew D
Publicado em 2008

Purification and Characterization of a Cellular Protein That Binds to the Downstream Activation Sequence of the Strict Late U(L)38 Promoter of Herpes Simplex Virus Type 1

Por Petroski, Matthew D., Wagner, Edward K.
Publicado em 1998

Urm1 couples sulfur transfer to ubiquitin-like protein function in oxidative stress

Por Petroski, Matthew D., Salvesen, Guy S., Wolf, Dieter A.
Publicado em 2011

K11- and K48-Linked Ubiquitin Chains Interact with p97 during Endoplasmic Reticulum-Associated Degradation

Por Locke, Matthew, Toth, Julia I., Petroski, Matthew D.
Publicado em 2014

The Cyclomodulin Cycle Inhibiting Factor (CIF) Alters Cullin Neddylation Dynamics

Por Toro, Tasha B., Toth, Julia I., Petroski, Matthew D.
Publicado em 2013

A gatekeeper residue for NEDD8 activating enzyme inhibition by MLN4924

Por Toth, Julia I., Yang, Li, Dahl, Russell, Petroski, Matthew D.
Publicado em 2012

Adapted ATPase domain communication overcomes the cytotoxicity of p97 inhibitors

Por Wei, Yang, Toth, Julia I., Blanco, Gabrielle A., Bobkov, Andrey A., Petroski, Matthew D.
Publicado no J Biol Chem (2018)

Regulation of Endoplasmic Reticulum-associated Degradation by RNF5-dependent Ubiquitination of JNK-associated Membrane Protein (JAMP)

Por Tcherpakov, Marianna, Delaunay, Agnes, Toth, Julia, Kadoya, Takayuki, Petroski, Matthew D., Ronai, Ze'ev A.
Publicado em 2009

Bifunctional Apoptosis Regulator (BAR), an Endoplasmic Reticulum (ER)-associated E3 Ubiquitin Ligase, Modulates BI-1 Protein Stability and Function in ER Stress

Por Rong, Juan, Chen, Lili, Toth, Julia I., Tcherpakov, Marianna, Petroski, Matthew D., Reed, John C.
Publicado em 2011

CAND1 controls in vivo dynamics of the Cullin 1-RING ubiquitin ligase repertoire

Por Wu, Shuangding, Zhu, Wenhong, Nhan, Tina, Toth, Julia I., Petroski, Matthew D., Wolf, Dieter A.
Publicado em 2013

N(6)-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

Por Wang, Yang, Li, Yue, Toth, Julia I., Petroski, Matthew D., Zhang, Zhaolei, Zhao, Jing Crystal
Publicado no Nat Cell Biol (2014)

p97 composition changes caused by allosteric inhibition are suppressed by an on-target mechanism that increases the enzyme’s ATPase activity

Por Her, Nam-Gu, Toth, Julia I., Ma, Chen-Ting, Wei, Yang, Motamedchaboki, Khatereh, Sergienko, Eduard, Petroski, Matthew D.
Publicado no Cell Chem Biol (2016)

REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A–DDB1 ubiquitin ligase

Por Katiyar, Samiksha, Liu, Enbo, Knutzen, Christine A, Lang, Elizabeth S, Lombardo, Christian R, Sankar, Sabita, Toth, Julia I, Petroski, Matthew D, Ronai, Ze'ev, Chiang, Gary G
Publicado em 2009

Single-particle EM reveals extensive conformational variability of the Ltn1 E3 ligase

Por Lyumkis, Dmitry, Doamekpor, Selom K., Bengtson, Mario H., Lee, Joong-Won, Toro, Tasha B., Petroski, Matthew D., Lima, Christopher D., Potter, Clinton S., Carragher, Bridget, Joazeiro, Claudio A. P.
Publicado em 2013

Mutations in UBA3 Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924 in Human Leukemic Cells

Por Xu, G. Wei, Toth, Julia I., da Silva, Sara R., Paiva, Stacey-Lynn, Lukkarila, Julie L., Hurren, Rose, Maclean, Neil, Sukhai, Mahadeo A., Bhattacharjee, Rabindra N., Goard, Carolyn A., Gunning, Patrick T., Dhe-Paganon, Sirano, Petroski, Matthew D., Schimmer, Aaron D.
Publicado em 2014