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The Cyclomodulin Cycle Inhibiting Factor (CIF) Alters Cullin Neddylation Dynamics
The bacterial effector protein cycle inhibiting factor (CIF) converts glutamine 40 of NEDD8 to glutamate (Q40E), causing cytopathic effects and inhibiting cell proliferation. Although these have been attributed to blocking the functions of cullin-RING ubiquitin ligases, how CIF modulates NEDD8-depen...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663497/ https://ncbi.nlm.nih.gov/pubmed/23589306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.448258 |
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