Control of mTORC1 signaling by the Opitz syndrome protein MID1

Mutations in the MID1 gene are causally linked to X-linked Opitz BBB/G syndrome (OS), a congenital disorder that primarily affects the formation of diverse ventral midline structures. The MID1 protein has been shown to function as an E3 ligase targeting the catalytic subunit of protein phosphatase 2...

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Bibliographic Details
Main Authors: Liu, Enbo, Knutzen, Christine A., Krauss, Sybille, Schweiger, Susann, Chiang, Gary G.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102420/
https://ncbi.nlm.nih.gov/pubmed/21555591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100131108
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