A braided cancer river connects tumor heterogeneity and precision medicine

Por Hsieh, James J., Cheng, Emily H.
Publicado no Clin Transl Med (2016)

The panoramic view of clear cell renal cell carcinoma metabolism: values of integrated global cancer metabolomics

Por Hsieh, James J., Cheng, Emily H.
Publicado no Transl Androl Urol (2016)

Taspase 1: A protease with many biological surprises

Por Niizuma, Hidetaka, Cheng, Emily H, Hsieh, James J
Publicado no Mol Cell Oncol (2015)

Bimodal degradation of MLL by SCF(Skp2) and APC(Cdc20) assures cell cycle execution: a critical regulatory circuit lost in leukemogenic MLL fusions

Por Liu, Han, Cheng, Emily H.-Y., Hsieh, James J.-D.
Publicado em 2007

BAK regulates catalase release from peroxisomes

Por Fujiki, Yukio, Miyata, Non, Mukai, Satoru, Okumoto, Kanji, Cheng, Emily H.
Publicado no Mol Cell Oncol (2017)

Proapoptotic BAX and BAK control multiple initiator caspases

Por Ruiz-Vela, Antonio, Opferman, Joseph T, Cheng, Emily H-Y, Korsmeyer, Stanley J
Publicado em 2005

SWI/SNF tumor suppressor gene PBRM1/BAF180 in human clear cell kidney cancer

Por Nargund, Amrita M., Osmanbeyoglu, Hatice U., Cheng, Emily H., Hsieh, James J.
Publicado no Mol Cell Oncol (2017)

Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy

Por Chen, Yun, Lewis, William, Diwan, Abhinav, Cheng, Emily H.-Y., Matkovich, Scot J., Dorn, Gerald W.
Publicado em 2010

The VDAC2–BAK axis regulates peroxisomal membrane permeability

Por Hosoi, Ken-ichiro, Miyata, Non, Mukai, Satoru, Furuki, Satomi, Okumoto, Kanji, Cheng, Emily H., Fujiki, Yukio
Publicado no J Cell Biol (2017)

Overcome Tumor Heterogeneity-Imposed Therapeutic Barriers through Convergent Genomic Biomarker Discovery: A Braided Cancer River Model of Kidney Cancer

Por Hsieh, James J., Manley, Brandon, Khan, Nabeela, Gao, JianJiong, Carlo, Maria I., Cheng, Emily H.
Publicado no Semin Cell Dev Biol (2016)

HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma

Por Takeda, Shugaku, Liu, Han, Sasagawa, Satoru, Dong, Yiyu, Trainor, Paul A., Cheng, Emily H., Hsieh, James J.
Publicado em 2013

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis

Por Dong, Yiyu, Van Tine, Brian A, Oyama, Toshinao, Wang, Patricia I, Cheng, Emily H, Hsieh, James J
Publicado no Cell Res (2014)

A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak

Por Cheng, Emily H.-Y., Nicholas, John, Bellows, David S., Hayward, Gary S., Guo, Hong-Guang, Reitz, Marvin S., Hardwick, J. Marie
Publicado em 1997

Cleavage of TFIIA by Taspase1 Activates TRF2-Specified Mammalian Male Germ Cell Programs

Por Oyama, Toshinao, Sasagawa, Satoru, Takeda, Shugaku, Hess, Rex A., Lieberman, Paul M., Cheng, Emily H., Hsieh, James J.
Publicado em 2013

Role of BH3-Only Molecules Bim and Puma in β-Cell Death in Pdx1 Deficiency

Por Ren, Decheng, Sun, Juan, Wang, Changzheng, Ye, Honggang, Mao, Liqun, Cheng, Emily H., Bell, Graeme I., Polonsky, Kenneth S.
Publicado em 2014

Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription

Por Takeda, Shugaku, Sasagawa, Satoru, Oyama, Toshinao, Searleman, Adam C., Westergard, Todd D., Cheng, Emily H., Hsieh, James J.
Publicado no J Clin Invest (2015)

Phosphorylation of MLL by ATR is Required for Execution of Mammalian S Phase Checkpoint

Por Liu, Han, Takeda, Shugaku, Kumar, Rakesh, Westergard, Todd D., Brown, Eric J., Pandita, Tej K., Cheng, Emily H.-Y., Hsieh, James J.-D.
Publicado em 2010

A new pathway that regulates 53BP1 stability implicates Cathepsin L and vitamin D in DNA repair

Por Gonzalez-Suarez, Ignacio, Redwood, Abena B, Grotsky, David A, Neumann, Martin A, Cheng, Emily H-Y, Stewart, Colin L, Dusso, Adriana, Gonzalo, Susana
Publicado em 2011

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

Por Kim, Hyungjin, Tu, Ho-Chou, Ren, Decheng, Takeuchi, Osamu, Jeffers, John R., Zambetti, Gerard P., Hsieh, James J.-D., Cheng, Emily H.-Y.
Publicado em 2009

A novel chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2

Por Palaniappan, Krishnan K., Hangauer, Matthew J., Smith, Timothy J., Smart, Brian P., Pitcher, Austin A., Cheng, Emily H., Bertozzi, Carolyn R., Boyce, Michael
Publicado em 2013