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Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy

Dysregulation of programmed cell death due to abnormal expression of Bcl-2 proteins is implicated in cancer, neurodegenerative diseases, and heart failure. Among Bcl-2 family members, BNip proteins uniquely stimulate cell death with features of both apoptosis and necrosis. Localization of these fact...

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Detalhes bibliográficos
Main Authors: Chen, Yun, Lewis, William, Diwan, Abhinav, Cheng, Emily H.-Y., Matkovich, Scot J., Dorn, Gerald W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889094/
https://ncbi.nlm.nih.gov/pubmed/20418503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914013107
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