Nix-mediated Apoptosis Links Myocardial Fibrosis, Cardiac Remodeling, and Hypertrophy Decompensation

BACKGROUND: Pathological cardiac hypertrophy inevitably remodels, leading to functional decompensation. Although modulation of apoptosis-regulating genes occurs in cardiac hypertrophy, a causal role for programmed cardiomyocyte death in left ventricular (LV) remodeling has not been established. METH...

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Autors principals: Diwan, Abhinav, Wansapura, Janaka, Syed, Faisal M., Matkovich, Scot J., Lorenz, John N., Dorn, Gerald W.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538800/
https://ncbi.nlm.nih.gov/pubmed/18178777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.107.727073
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