MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure overloaded adult hearts

RATIONALE: microRNA (miR)-133a regulates cardiac and skeletal muscle differentiation and plays an important role in cardiac development. Because miR-133a levels decrease during reactive cardiac hypertrophy, some have considered that restoring miR-133a levels could suppress hypertrophic remodeling. O...

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Main Authors: Matkovich, Scot J, Wang, Wei, Tu, Yizheng, Eschenbacher, William H, Dorn, Lisa E, Condorelli, Gianluigi, Diwan, Abhinav, Nerbonne, Jeanne M, Dorn, Gerald W
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804031/
https://ncbi.nlm.nih.gov/pubmed/19893015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.202176
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