Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription

Head morphogenesis requires complex signal relays to enable precisely coordinated proliferation, migration, and patterning. Here, we demonstrate that, during mouse head formation, taspase1-mediated (TASP1-mediated) cleavage of the general transcription factor TFIIA ensures proper coordination of rap...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Takeda, Shugaku, Sasagawa, Satoru, Oyama, Toshinao, Searleman, Adam C., Westergard, Todd D., Cheng, Emily H., Hsieh, James J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362222/
https://ncbi.nlm.nih.gov/pubmed/25664857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77075
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