Uncleaved TFIIA Is a Substrate for Taspase 1 and Active in Transcription

In higher eukaryotes, the large subunit of the general transcription factor TFIIA is encoded by the single TFIIAαβ gene and posttranslationally cleaved into α and β subunits. The molecular mechanisms and biological significance of this proteolytic process have remained obscure. Here, we show that TF...

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Detalhes bibliográficos
Main Authors: Zhou, Huiqing, Spicuglia, Salvatore, Hsieh, James J.-D., Mitsiou, Dimitra J., Høiby, Torill, Veenstra, Gert Jan C., Korsmeyer, Stanley J., Stunnenberg, Hendrik G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430320/
https://ncbi.nlm.nih.gov/pubmed/16537915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.7.2728-2735.2006
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