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Cleavage and proteasome-mediated degradation of the basal transcription factor TFIIA

The transcription factor TFIIA is encoded by two genes, TFIIAαβ and TFIIAγ. In higher eukaryotes, the TFIIAαβ is translated as a precursor and undergoes proteolytic cleavage; the regulation and biological implications of the cleavage have remained elusive. We determined by Edman degradation that the...

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Detaylı Bibliyografya
Asıl Yazarlar: Høiby, Torill, Mitsiou, Dimitra J, Zhou, Huiqing, Erdjument-Bromage, Hediye, Tempst, Paul, Stunnenberg, Hendrik G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC514921/
https://ncbi.nlm.nih.gov/pubmed/15257296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600304
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