تحميل...
Proteasome-Mediated Processing of Def1, a Critical Step in the Cellular Response to Transcription Stress
DNA damage triggers polyubiquitylation and degradation of the largest subunit of RNA polymerase II (RNAPII), a “mechanism of last resort” employed during transcription stress. In yeast, this process is dependent on Def1 through a previously unresolved mechanism. Here, we report that Def1 becomes act...
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| المؤلفون الرئيسيون: | , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Cell Press
2013
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778974/ https://ncbi.nlm.nih.gov/pubmed/23993092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.07.028 |
| الوسوم: |
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