Učitavanje...
Taspase1 Functions as a Non-oncogene Addiction Protease that Coordinates Cancer Cell Proliferation and Apoptosis
Taspase1 (TASP-1), the MLL and TFIIAα-β cleaving protease, enables cell proliferation and permits oncogenic initiation. Here, we demonstrate its critical role in cancer maintenance and thus offer a new anticancer target. Taspase1 is over-expressed in primary human cancers and deficiency of Taspase1...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909739/ https://ncbi.nlm.nih.gov/pubmed/20516119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0027 |
| Oznake: |
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