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Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription

Head morphogenesis requires complex signal relays to enable precisely coordinated proliferation, migration, and patterning. Here, we demonstrate that, during mouse head formation, taspase1-mediated (TASP1-mediated) cleavage of the general transcription factor TFIIA ensures proper coordination of rap...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Takeda, Shugaku, Sasagawa, Satoru, Oyama, Toshinao, Searleman, Adam C., Westergard, Todd D., Cheng, Emily H., Hsieh, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362222/
https://ncbi.nlm.nih.gov/pubmed/25664857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77075
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