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Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis
Taspase1, a highly conserved threonine protease, cleaves nuclear transcriptional regulators mixed-lineage leukemia (MLL, MLL1), MLL2, TFIIA, and ALF to orchestrate a wide variety of biological processes. In vitro studies thus far demonstrated that Taspase1 plays important roles in the proliferation...
Shranjeno v:
| izdano v: | Cell Res |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4220155/ https://ncbi.nlm.nih.gov/pubmed/25267403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.129 |
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