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Dmp1α Inhibits HER2/neu-Induced Mammary Tumorigenesis
Our recent study shows a pivotal role of Dmp1 in quenching hyperproliferative signals from HER2 to the Arf-p53 pathway as a safety mechanism to prevent breast carcinogenesis. To directly demonstrate the role of Dmp1 in preventing HER2/neu-driven oncogenic transformation, we established Flag-Dmp1α tr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812138/ https://ncbi.nlm.nih.gov/pubmed/24205004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077870 |
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