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Oncogenic and tumor-suppressive mouse models for breast cancer engaging HER2/neu
The human c-ErbB2 (HER2) gene is amplified in ~20 % of human breast cancers (BCs), but the protein is overexpressed in ~30% of the cases indicating that multiple different mechanisms contribute to HER2 overexpression in tumors. It has long been used as a molecular marker of BC for sub-categorization...
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| Опубликовано в: : | Int J Cancer |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5159240/ https://ncbi.nlm.nih.gov/pubmed/27553713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30399 |
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