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Oncogenic and tumor-suppressive mouse models for breast cancer engaging HER2/neu

The human c-ErbB2 (HER2) gene is amplified in ~20 % of human breast cancers (BCs), but the protein is overexpressed in ~30% of the cases indicating that multiple different mechanisms contribute to HER2 overexpression in tumors. It has long been used as a molecular marker of BC for sub-categorization...

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Publicat a:Int J Cancer
Autors principals: Fry, Elizabeth A., Taneja, Pankaj, Inoue, Kazushi
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159240/
https://ncbi.nlm.nih.gov/pubmed/27553713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30399
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