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Overcome Tumor Heterogeneity-Imposed Therapeutic Barriers through Convergent Genomic Biomarker Discovery: A Braided Cancer River Model of Kidney Cancer
Tumor heterogeneity, encompassing genetic, epigenetic, and microenvironmental variables, is extremely complex and presents challenges to cancer diagnosis and therapy. Genomic efforts on genetic intratumor heterogeneity (G-ITH) confirm branched evolution, support the trunk-branch cancer model, and pr...
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| Publicado no: | Semin Cell Dev Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522717/ https://ncbi.nlm.nih.gov/pubmed/27615548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2016.09.002 |
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