Anti-CD22/CD20 Bispecific Antibody with Enhanced Trogocytosis for Treatment of Lupus

Por Rossi, Edmund A., Chang, Chien-Hsing, Goldenberg, David M.
Publicado em 2014

Monoclonal antibodies targeting CD20

Por Chang, Chien-Hsing, Rossi, Edmund A., Goldenberg, David M.
Publicado em 2013

Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells

Por Chang, Chien-Hsing, Wang, Yang, Gupta, Pankaj, Goldenberg, David M
Publicado no MAbs (2014)

Multiple signaling pathways induced by hexavalent, monospecific, anti-CD20 and hexavalent, bispecific, anti-CD20/CD22 humanized antibodies correlate with enhanced toxicity to B-cel...

Por Gupta, Pankaj, Goldenberg, David M., Rossi, Edmund A., Chang, Chien-Hsing
Publicado em 2010

Identification of PAM4 (clivatuzumab)-reactive epitope on MUC5AC: A promising biomarker and therapeutic target for pancreatic cancer

Por Liu, Donglin, Chang, Chien-Hsing, Gold, David V., Goldenberg, David M.
Publicado no Oncotarget (2015)

Improved Cancer Therapy and Molecular Imaging with Multivalent, Multispecific Antibodies

Por Sharkey, Robert M., Rossi, Edmund A., Chang, Chien-Hsing, Goldenberg, David M.
Publicado em 2010

Targeting both IGF-1R and mTOR synergistically inhibits growth of renal cell carcinoma in vitro

Por Cardillo, Thomas M, Trisal, Preeti, Arrojo, Roberto, Goldenberg, David M, Chang, Chien-Hsing
Publicado em 2013

In-Vivo Fusion of Human Cancer and Hamster Stromal Cells Permanently Transduces and Transcribes Human DNA

Por Goldenberg, David M., Rooney, Robert J., Loo, Meiyu, Liu, Donglin, Chang, Chien-Hsing
Publicado em 2014

Hexavalent bispecific antibodies represent a new class of anticancer therapeutics: 1. Properties of anti-CD20/CD22 antibodies in lymphoma

Por Rossi, Edmund A., Goldenberg, David M., Cardillo, Thomas M., Stein, Rhona, Chang, Chien-Hsing
Publicado em 2009

CD20-targeted tetrameric interferon-α, a novel and potent immunocytokine for the therapy of B-cell lymphomas

Por Rossi, Edmund A., Goldenberg, David M., Cardillo, Thomas M., Stein, Rhona, Chang, Chien-Hsing
Publicado em 2009

Interferon-λ1 Linked to a Stabilized Dimer of Fab Potently Enhances both Antitumor and Antiviral Activities in Targeted Cells

Por Liu, Donglin, Chang, Chien-Hsing, Rossi, Edmund A., Cardillo, Thomas M., Goldenberg, David M.
Publicado em 2013

Horizontal Transmission of Malignancy: In-Vivo Fusion of Human Lymphomas with Hamster Stroma Produces Tumors Retaining Human Genes and Lymphoid Pathology

Por Goldenberg, David M., Gold, David V., Loo, Meiyu, Liu, Donglin, Chang, Chien-Hsing, Jaffe, Elaine S.
Publicado em 2013

A new class of bispecific antibodies to redirect T cells for cancer immunotherapy

Por Rossi, Diane L, Rossi, Edmund A, Cardillo, Thomas M, Goldenberg, David M, Chang, Chien-Hsing
Publicado em 2014

Bispecific anti-CD20/22 antibodies inhibit B-cell lymphoma proliferation by a unique mechanism of action

Por Qu, Zhengxing, Goldenberg, David M., Cardillo, Thomas M., Shi, Victoria, Hansen, Hans J., Chang, Chien-Hsing
Publicado em 2008

Recombinant Bispecific Monoclonal Antibodies Prepared by the Dock-and-Lock Strategy for Pretargeted Radioimmunotherapy

Por Sharkey, Robert M., Rossi, Edmund A., McBride, William J., Chang, Chien-Hsing, Goldenberg, David M.
Publicado em 2010

Pretargeted Molecular Imaging and Radioimmunotherapy

Por Goldenberg, David M., Chang, Chien-Hsing, Rossi, Edmund A., J, William, McBride, Sharkey, Robert M.
Publicado em 2012

Trop-2-targeting tetrakis-ranpirnase has potent antitumor activity against triple-negative breast cancer

Por Liu, Donglin, Cardillo, Thomas M, Wang, Yang, Rossi, Edmund A, Goldenberg, David M, Chang, Chien-Hsing
Publicado em 2014

Preclinical studies on targeted delivery of multiple IFNα2b to HLA-DR in diverse hematologic cancers

Por Rossi, Edmund A., Rossi, Diane L., Cardillo, Thomas M., Stein, Rhona, Goldenberg, David M., Chang, Chien-Hsing
Publicado em 2011

Stably tethered multifunctional structures of defined composition made by the dock and lock method for use in cancer targeting

Por Rossi, Edmund A., Goldenberg, David M., Cardillo, Thomas M., McBride, William J., Sharkey, Robert M., Chang, Chien-Hsing
Publicado em 2006

Therapy of B-cell malignancies by anti–HLA-DR humanized monoclonal antibody, IMMU-114, is mediated through hyperactivation of ERK and JNK MAP kinase signaling pathways

Por Stein, Rhona, Gupta, Pankaj, Chen, Xiaochuan, Cardillo, Thomas M., Furman, Richard R., Chen, Susan, Chang, Chien-Hsing, Goldenberg, David M.
Publicado em 2010