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Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells

Epratuzumab has demonstrated therapeutic activity in patients with non-Hodgkin lymphoma, acute lymphoblastic leukemia, systemic lupus erythematosus, and Sjögren's syndrome, but its mechanism of affecting normal and malignant B cells remains incompletely understood. We reported previously that e...

詳細記述

保存先:
書誌詳細
出版年:MAbs
主要な著者: Chang, Chien-Hsing, Wang, Yang, Gupta, Pankaj, Goldenberg, David M
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622945/
https://ncbi.nlm.nih.gov/pubmed/25484043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2014.979081
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