Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus

B cells play an important role in the pathogenesis of systemic lupus erythematosus (SLE), so the safety and activity of anti-B cell immunotherapy with the humanized anti-CD22 antibody epratuzumab was evaluated in SLE patients. An open-label, single-center study of 14 patients with moderately active...

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Bibliographische Detailangaben
Hauptverfasser: Dörner, Thomas, Kaufmann, Joerg, Wegener, William A, Teoh, Nick, Goldenberg, David M, Burmester, Gerd R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2006
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526638/
https://ncbi.nlm.nih.gov/pubmed/16630358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1942
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