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Anti-CD22/CD20 Bispecific Antibody with Enhanced Trogocytosis for Treatment of Lupus

The humanized anti-CD22 antibody, epratuzumab, has demonstrated therapeutic activity in clinical trials of lymphoma, leukemia and autoimmune diseases, treating currently over 1500 cases of non-Hodgkin lymphoma, acute lymphoblastic leukemias, Waldenström’s macroglobulinemia, Sjögren’s syndrome, and s...

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Bibliographic Details
Main Authors: Rossi, Edmund A., Chang, Chien-Hsing, Goldenberg, David M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026529/
https://ncbi.nlm.nih.gov/pubmed/24841238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098315
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