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Stably tethered multifunctional structures of defined composition made by the dock and lock method for use in cancer targeting

We describe a platform technology, termed the dock and lock method, which uses a natural binding between the regulatory subunits of cAMP-dependent protein kinase and the anchoring domains of A kinase anchor proteins for general application in constructing bioactive conjugates of different protein an...

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Autores principales: Rossi, Edmund A., Goldenberg, David M., Cardillo, Thomas M., McBride, William J., Sharkey, Robert M., Chang, Chien-Hsing
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1447525/
https://ncbi.nlm.nih.gov/pubmed/16636283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600982103
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