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Stably tethered multifunctional structures of defined composition made by the dock and lock method for use in cancer targeting
We describe a platform technology, termed the dock and lock method, which uses a natural binding between the regulatory subunits of cAMP-dependent protein kinase and the anchoring domains of A kinase anchor proteins for general application in constructing bioactive conjugates of different protein an...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1447525/ https://ncbi.nlm.nih.gov/pubmed/16636283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600982103 |
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