CD20-targeted tetrameric interferon-α, a novel and potent immunocytokine for the therapy of B-cell lymphomas

Interferon-α (IFN-α) has direct inhibitory effects on some tumors and is a potent stimulator of both the innate and adaptive immune systems. A tumor-targeting antibody-IFN-α conjugate (mAb-IFN-α) could kill by direct actions of the monoclonal antibody (mAb) and IFN-α on tumor cells and also potentia...

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Bibliografiske detaljer
Main Authors: Rossi, Edmund A., Goldenberg, David M., Cardillo, Thomas M., Stein, Rhona, Chang, Chien-Hsing
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773491/
https://ncbi.nlm.nih.gov/pubmed/19710501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-228890
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