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CD20-targeted tetrameric interferon-α, a novel and potent immunocytokine for the therapy of B-cell lymphomas
Interferon-α (IFN-α) has direct inhibitory effects on some tumors and is a potent stimulator of both the innate and adaptive immune systems. A tumor-targeting antibody-IFN-α conjugate (mAb-IFN-α) could kill by direct actions of the monoclonal antibody (mAb) and IFN-α on tumor cells and also potentia...
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Główni autorzy: | , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society of Hematology
2009
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773491/ https://ncbi.nlm.nih.gov/pubmed/19710501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-228890 |
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