Horizontal Transmission of Malignancy: In-Vivo Fusion of Human Lymphomas with Hamster Stroma Produces Tumors Retaining Human Genes and Lymphoid Pathology

We report the in-vivo fusion of two Hodgkin lymphomas with golden hamster cheek pouch cells, resulting in serially-transplanted (over 5–6 years) GW-532 and GW-584 heterosynkaryon tumor cells displaying both human and hamster DNA (by FISH), lymphoma-like morphology, aggressive metastasis, and retenti...

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Detaylı Bibliyografya
Asıl Yazarlar: Goldenberg, David M., Gold, David V., Loo, Meiyu, Liu, Donglin, Chang, Chien-Hsing, Jaffe, Elaine S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566191/
https://ncbi.nlm.nih.gov/pubmed/23405135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055324
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