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Interferon-λ1 Linked to a Stabilized Dimer of Fab Potently Enhances both Antitumor and Antiviral Activities in Targeted Cells

The type III interferons (IFNs), comprising IFN-λ1, IFN-λ2, and IFN-λ3, behave similarly to IFN-α in eliciting antiviral, antitumor, and immune-modulating activities. Due to their more restricted cellular targets, IFN-λs are attractive as potential alternatives to existing therapeutic regimens based...

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Main Authors: Liu, Donglin, Chang, Chien-Hsing, Rossi, Edmund A., Cardillo, Thomas M., Goldenberg, David M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655979/
https://ncbi.nlm.nih.gov/pubmed/23696859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063940
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