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Selective Janus Kinase Inhibition Preserves Interferon-Λ-mediated Antiviral Responses
Inflammatory diseases are frequently treated with Janus kinase (JAK) inhibitors to diminish cytokine signaling. These treatments can lead to inadvertent immune suppression and may increase the risk of viral infection. Tyrosine kinase 2 (TYK2) is a JAK family member required for efficient type I inte...
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| 出版年: | Sci Immunol |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610871/ https://ncbi.nlm.nih.gov/pubmed/33990378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abd5318 |
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