IFNλ is a potent anti‐influenza therapeutic without the inflammatory side effects of IFNα treatment

Influenza A virus (IAV)‐induced severe disease is characterized by infected lung epithelia, robust inflammatory responses and acute lung injury. Since type I interferon (IFNαβ) and type III interferon (IFNλ) are potent antiviral cytokines with immunomodulatory potential, we assessed their efficacy a...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Davidson, Sophia, McCabe, Teresa M, Crotta, Stefania, Gad, Hans Henrik, Hessel, Edith M, Beinke, Soren, Hartmann, Rune, Wack, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009813/
https://ncbi.nlm.nih.gov/pubmed/27520969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606413
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