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Selective Janus Kinase Inhibition Preserves Interferon-Λ-mediated Antiviral Responses
Inflammatory diseases are frequently treated with Janus kinase (JAK) inhibitors to diminish cytokine signaling. These treatments can lead to inadvertent immune suppression and may increase the risk of viral infection. Tyrosine kinase 2 (TYK2) is a JAK family member required for efficient type I inte...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Sci Immunol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610871/ https://ncbi.nlm.nih.gov/pubmed/33990378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abd5318 |
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