Small Molecule Probes of Cellular Pathways and Networks

Por Castoreno, Adam B., Eggert, Ulrike S.
Publicado em 2010

Modulation of Endosomal Cholesteryl Ester Metabolism by Membrane Cholesterol

Por Wang, Yan, Castoreno, Adam B., Stockinger, Walter, Nohturfft, Axel
Publicado em 2005

Making the cut: The chemical biology of cytokinesis

Por Atilla-Gokcumen, G. Ekin, Castoreno, Adam B., Sasse, Sofia, Eggert, Ulrike S.
Publicado em 2010

Real-time analysis of endosomal lipid transport by live cell scintillation proximity assay

Por Stockinger, Walter, Castoreno, Adam B., Wang, Yan, Pagnon, Joanne C., Nohturfft, Axel
Publicado em 2004

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis

Por Castoreno, Adam B., Smurnyy, Yegor, Torres, Angelica D., Vokes, Martha S., Jones, Thouis R., Carpenter, Anne E., Eggert, Ulrike S.
Publicado em 2010

Transcriptional regulation of phagocytosis-induced membrane biogenesis by sterol regulatory element binding proteins

Por Castoreno, Adam B., Wang, Yan, Stockinger, Walter, Jarzylo, Larissa A., Du, Hong, Pagnon, Joanne C., Shieh, Eugenie C., Nohturfft, Axel
Publicado em 2005

Differential Requirements for Actin Polymerization, Calmodulin, and Ca(2+) Define Distinct Stages of Lysosome/Phagosome Targeting

Por Stockinger, Walter, Zhang, Shao C., Trivedi, Vishal, Jarzylo, Larissa A., Shieh, Eugenie C., Lane, William S., Castoreno, Adam B., Nohturfft, Axel
Publicado em 2006

Immunoglobulin G signaling activates lysosome/phagosome docking

Por Trivedi, Vishal, Zhang, Shao C., Castoreno, Adam B., Stockinger, Walter, Shieh, Eugenie C., Vyas, Jatin M., Frickel, Eva-Maria, Nohturfft, Axel
Publicado em 2006

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning

Por Jones, Thouis R., Carpenter, Anne E., Lamprecht, Michael R., Moffat, Jason, Silver, Serena J., Grenier, Jennifer K., Castoreno, Adam B., Eggert, Ulrike S., Root, David E., Golland, Polina, Sabatini, David M.
Publicado em 2009

Discovery of a Small-Molecule Probe for V-ATPase Function

Por Aldrich, Leslie N., Kuo, Szu-Yu, Castoreno, Adam B., Goel, Gautam, Kuballa, Petric, Rees, Matthew G., Seashore-Ludlow, Brinton A., Cheah, Jaime H., Latorre, Isabel J., Schreiber, Stuart L., Shamji, Alykhan F., Xavier, Ramnik J.
Publicado no J Am Chem Soc (2015)

Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity

Por Janas, Maja M., Schlegel, Mark K., Harbison, Carole E., Yilmaz, Vedat O., Jiang, Yongfeng, Parmar, Rubina, Zlatev, Ivan, Castoreno, Adam, Xu, Huilei, Shulga-Morskaya, Svetlana, Rajeev, Kallanthottathil G., Manoharan, Muthiah, Keirstead, Natalie D., Maier, Martin A., Jadhav, Vasant
Publicado no Nat Commun (2018)

Selective modulation of autophagy, innate immunity and adaptive immunity by small molecules

Por Shaw, Stanley Y., Tran, Khoa, Castoreno, Adam B., Peloquin, Joanna M., Lassen, Kara G., Khor, Bernard, Aldrich, Leslie N., Tan, Pauline H., Graham, Daniel B., Kuballa, Petric, Goel, Gautam, Daly, Mark J., Shamji, Alykhan F., Schreiber, Stuart L., Xavier, Ramnik J.
Publicado em 2013

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

Por Kuo, Szu-Yu, Castoreno, Adam B., Aldrich, Leslie N., Lassen, Kara G., Goel, Gautam, Dančík, Vlado, Kuballa, Petric, Latorre, Isabel, Conway, Kara L., Sarkar, Sovan, Maetzel, Dorothea, Jaenisch, Rudolf, Clemons, Paul A., Schreiber, Stuart L., Shamji, Alykhan F., Xavier, Ramnik J.
Publicado no Proc Natl Acad Sci U S A (2015)

Autophagy inhibition dysregulates TBK1 signaling and promotes pancreatic inflammation

Por Yang, Shenghong, Imamura, Yu, Jenkins, Russell W., Cañadas, Israel, Kitajima, Shunsuke, Aref, Amir, Brannon, Arthur, Oki, Eiji, Castoreno, Adam, Zhu, Zehua, Thai, Tran, Reibel, Jacob, Qian, Zhirong, Ogino, Shuji, Wong, Kwok K., Baba, Hideo, Kimmelman, Alec C., Di Magliano, Marina Pasca, Barbie, David A.
Publicado no Cancer Immunol Res (2016)

Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection

Por Conway, Kara L., Kuballa, Petric, Song, Joo-Hye, Patel, Khushbu K., Castoreno, Adam B., Yilmaz, Omer H., Jijon, Humberto B., Zhang, Mei, Aldrich, Leslie N., Villablanca, Eduardo J., Peloquin, Joanna M., Goel, Gautam, Lee, In-Ah, Mizoguchi, Emiko, Shi, Hai Ning, Bhan, Atul K., Shaw, Stanley Y., Schreiber, Stuart L., Virgin, Herbert W., Shamji, Alykhan F., Stappenbeck, Thaddeus S., Reinecker, Hans C., Xavier, Ramnik J.
Publicado em 2013