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Immunoglobulin G signaling activates lysosome/phagosome docking

An important role of IgG antibodies in the defense against microbial infections is to promote the ingestion and killing of microbes by phagocytes. Here, we developed in vivo and in vitro approaches to ask whether opsonization of particles with IgG enhances intracellular targeting of lysosomes to pha...

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Detalhes bibliográficos
Main Authors: Trivedi, Vishal, Zhang, Shao C., Castoreno, Adam B., Stockinger, Walter, Shieh, Eugenie C., Vyas, Jatin M., Frickel, Eva-Maria, Nohturfft, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838734/
https://ncbi.nlm.nih.gov/pubmed/17110435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609182103
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