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Immunoglobulin G signaling activates lysosome/phagosome docking

An important role of IgG antibodies in the defense against microbial infections is to promote the ingestion and killing of microbes by phagocytes. Here, we developed in vivo and in vitro approaches to ask whether opsonization of particles with IgG enhances intracellular targeting of lysosomes to pha...

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Autors principals: Trivedi, Vishal, Zhang, Shao C., Castoreno, Adam B., Stockinger, Walter, Shieh, Eugenie C., Vyas, Jatin M., Frickel, Eva-Maria, Nohturfft, Axel
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838734/
https://ncbi.nlm.nih.gov/pubmed/17110435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609182103
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