Discovery of a Small-Molecule Probe for V-ATPase Function

[Image: see text] Lysosomes perform a critical cellular function as a site of degradation for diverse cargoes including proteins, organelles, and pathogens delivered through distinct pathways, and defects in lysosomal function have been implicated in a number of diseases. Recent studies have elucida...

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Foilsithe in:J Am Chem Soc
Main Authors: Aldrich, Leslie N., Kuo, Szu-Yu, Castoreno, Adam B., Goel, Gautam, Kuballa, Petric, Rees, Matthew G., Seashore-Ludlow, Brinton A., Cheah, Jaime H., Latorre, Isabel J., Schreiber, Stuart L., Shamji, Alykhan F., Xavier, Ramnik J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2015
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416280/
https://ncbi.nlm.nih.gov/pubmed/25860544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b02150
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